Corrupt cops Divinci (James Belushi) and Rodriguez (Tupac Shakur) have been murdering drug dealers and then selling their narcotics. But they accidentally kill an undercover DEA agent, and soon after the murder, the dead man's partner, Simms (Gary Cole), comes calling. In search of a scapegoat, Divinci and Rodriguez find a homeless alcoholic they call Joe Doe (Dennis Quaid). But keeping up the scheme becomes increasingly dangerous and complex, and the DEA grows suspicious of the crooked duo.